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Category: Francis Crick Institute

Francis Crick researchers reveal pathways linking intestinal inflammation and colitis

Affecting over 500,000 people in the UK, IBD comprises Crohn’s disease and ulcerative colitis

April 15, 2024 Blimp-1, Crohn’s disease, Francis Crick Institute, IL-10, Inflammatory Bowel Disease, News, Ulcerative Colitis

Study suggests tumour microenvironments could predict cancer progression

NSCLC is the most common type of lung cancer and is responsible for up to 85% of all […]

April 12, 2024 Bristol Myers Squibb, Cancer Research UK, Francis Crick Institute, lung cancer, News, non-small cell lung cancer, Oncology, TRACERx, University College London

Francis Crick researchers target cancer cells’ ability to survive at low oxygen levels

LDHA and GOT1 enzymes successfully targeted and halted energy production in hard-to-reach cancer cells

March 25, 2024 cancer cells, Francis Crick Institute, glycolysis, GOT1, HIF1α, News, Oncology

Researchers identify new treatment target for genetic epilepsy

The rare neurodevelopmental condition CDKL5 is characterised by early-onset epilepsy

February 10, 2024 CDKL5, cyclin-dependent kinase-like 5 deficiency disorder, Francis Crick Institute, genetic epilepsy, Loulou Foundation, News

Researchers identify gene that causes heart defects in Down syndrome

Around 50% of babies born with the condition are affected by heart defects

January 25, 2024 Down syndrome, Dyrk1a, Francis Crick Institute, News, University College London

Immune cell helps predict skin cancer patients’ responses to immunotherapies

Vd1-gd T cells were effective in predicting positive responses to ICI therapy

January 5, 2024 Francis Crick Institute, Guy’s and St Thomas’ Hospital Trust, immune checkpoint inhibitors, King’s College London, melanoma, News, Oncology, skin cancer, Vd1-gd T cells

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